Thoughtful choices in designing patient rooms potentially contribute to reduced healthcare-associated infections and better HCAHPS scores. This presentation will introduce the results of important scientific studies, examining patient room materials including wood, stainless steel, and solid surfaces. Surfaces were tested before and after being compromised to simulate healthcare environments. Attendees will hear the candid, real world challenges of maintaining high design in the harsh healthcare environment that battles constant chemical cleaners and abuse. Attendees will explore how to “dollarize” the risk to hospitals based on Medicare reimbursements and discover avenues to merge science with style.